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We construct cobordism maps for the version of instanton knot homology associated to a knot cobordisms of arbitrary genus between two null-homologous knots in closed oriented -manifolds. As an application of our construction, we recover an inequality between the torsion order of knots in instanton theory, which was originally established in Heegaard Floer theory by work of Juhász, Miller, and Zemke. We further use this inequality to compute the framed instanton Floer homology of any non-zero Dehn surgeries along an alternating knot of bridge index at most .

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