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We consider necessary conditions and sufficient conditions on the solvability of the Cauchy–Dirichlet problem for a fractional semilinear heat equation in open sets (possibly unbounded and disconnected) with a smooth boundary. Our conditions enable us to identify the optimal strength of the admissible singularity of initial data for the local-in-time solvability and they differ in the interior of the set and on the boundary of the set.

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