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In this article, we study the Schrödinger-Newton equation \begin{equation} -Δu+λu=\frac{1}{4π}\left(\frac{1}{|x|}\star u^{2}\right)u+|u|^{q-2}u \quad ~^3, \end{equation} where , . By investigating limit profiles of ground states as or , we prove the uniqueness of ground states. By the action of the linearized eqaution with respect to decomposition into spherical harmonics, we obtain the nondegeneracy of ground states.

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