We consider a run-and-tumble particle (RTP) in one dimension, subjected to a telegraphic noise with a constant rate , and in the presence of an external confining potential with . We compute the mean first-passage time (MFPT) at the origin for an RTP starting at . We obtain a closed form expression for for all , which becomes fully explicit in the case , and in the limit . For generic we find that there exists an optimal rate that minimizes the MFPT and we characterize in detail its dependence on . We find that as , while converges to a nontrivial constant as . In contrast, for , there is no finite optimum and in this case. These analytical results are confirmed by our numerical simulations.

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