Non-integer characterizing slopes and knot Floer homology

Conjecturally, a knot in the 3-sphere has only finitely many non-integer non-characterizing slopes. We verify this conjecture for all knots with knot Floer homology satisfying certain simplicity conditions. The class of knots satisfying our notion of simplicity includes alternating knots, $L$-space knots and the vast majority of knots with at most 12 crossings. For arbitrary knots in the 3-sphere we show that almost all slopes $p\mathrm{/}q$ with $\mathrm{\mid }q\mathrm{\mid }\ge 3$ are characterizing. In addition, we show that all $L$-space knots and almost $L$-space knots have infinitely many integer characterizing slopes.