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In this paper, we consider a fourth order inner-controlled parabolic equation on an open bounded subset of , or a smooth compact manifold with boundary, along with general boundary operators fulfilling the Lopatinskii-Sapiro condition. We derive a spectral inequality for the solution of the parabolic system that yields a null-controllability result. The spectral inequality is a consequence of an interpolation inequality obtained via a Carleman inequality for the bi-Laplace operator under the considered boundary conditions.

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