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We study the impact of the two-loop corrections controlled by the BSM Higgs couplings on the cross section for the production of a pair of SM-like Higgs bosons via gluon fusion in the aligned THDM. To this aim, we reassess the two-loop calculation of , we compute for the first time the two-loop corrections to , and we include the relevant corrections to the Higgs-gluon couplings and to the s-channel propagators entering the amplitude. We discuss the numerical impact of the two-loop BSM contributions, first on the individual couplings and then on the prediction for the pair-production cross section, in two benchmark scenarios for the aligned THDM.

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