We study a thermodynamically consistent diffuse interface model that describes the motion of a two-phase flow of two viscous incompressible Newtonian fluids with unmatched densities and a soluble surfactant in a bounded domain of two or three dimensions. The resulting hydrodynamic system consists of a nonhomogeneous Navier-Stokes system for the (volume averaged) velocity and a coupled Cahn-Hilliard system for the phase-field variables and that represent the difference in volume fractions of the binary fluids and the surfactant concentration, respectively. For the initial boundary value problem with physically relevant singular potentials subject to a no-slip boundary condition for the fluid velocity and homogeneous Neumann boundary conditions for the phase-field variables and the chemical potentials, we first establish the existence of global weak solutions in the case of non-degenerate mobilities based on a suitable semi-implicit time discretization. Next, we prove the existence of global weak solutions for a class of general degenerate mobilities, with the aid of a new type of approximations for both the mobilities and the singular parts of the potential densities.

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