This work investigates the optimal control of the variable-exponent subdiffusion, which extends the work [Gunzburger and Wang, {\it SIAM J. Control Optim.} 2019] to the variable-exponent case to account for the multiscale and crossover diffusion behavior. To resolve the difficulties caused by the leading variable-exponent operator, we adopt the convolution method to reformulate the model into an equivalent but more tractable form, and then prove the well-posedness and weighted regularity of the optimal control. As the convolution kernels in reformulated models are indefinite-sign, non-positive-definite, and non-monotonic, we adopt the discrete convolution kernel approach in numerical analysis to show the accuracy of the schemes for state and adjoint equations. Numerical experiments are performed to substantiate the theoretical findings.

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