We study the images of polynomial maps over algebraically closed division rings. Our first result generalizes the classical Ax-Grothendieck theorem: We show that if are elements of the free associative algebra generated by variables over an algebraically closed division ring of finite dimension over its center , and if the induced map is injective, then must be surjective. With no condition on the dimension over the center, our second result is that if is either an element in with zero constant term such that , or a nonconstant polynomial in . Furthermore, we also establish some Waring type results. For instance, for any integer , we prove that every matrix in can be expressed as a difference of pairs of multiplicative commutators of elements from , provided again that is finite-dimensional over .

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