We investigate a system of nonlinear partial differential equations modeling the unsteady flow of a shear-thinning non-Newtonian fluid with a concentration-dependent power-law index. The system consists of the generalized Navier-Stokes equations coupled with a convection-diffusion equation describing the evolution of chemical concentration. This model arises from the mathematical description of the behavior of synovial fluid in the cavities of articulating joints. We prove the existence of a local-in-time strong solution in a three-dimensional spatially periodic domain, assuming that , where denotes the variable power-law index and and are its lower and upper bounds, respectively. Furthermore, we prove the uniqueness of the solution under the additional condition . In particular, our three-dimensional analysis directly implies the existence and uniqueness of solutions in the two-dimensional case under the less restrictive condition .

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