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Let be a connected simply connected semisimple complex algebraic group and a parabolic subgroup. We give a necessary and sufficient condition for a line bundle – on the blow-up of the generalized flag variety along a smooth Schubert variety – to be ample (respectively, nef). Furthermore, it is shown that every such nef line bundle is actually globally generated. As a consequence, we are able to describe when such a blow-up is (weak) Fano.

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