Modern quantum hardware exposes heterogeneous two-qubit instruction sets through fractional, continuously parameterized, and per-pair native gates, but synthesis remains largely framed around CNOT and a small catalog of closed-form rules. We present (Global Unitary Linear Programming Synthesis), a two-qubit compiler that partitions synthesis into depth- segments and uses a linear program over quantum Littlewood–Richardson reachability inequalities to plant the intermediate invariants between them. Each segment becomes an independent low-dimensional least-squares fit, solved by a Gauss–Newton/Levenberg–Marquardt routine. On Haar-random two-qubit targets, GULPS is more than faster than the general-purpose synthesizers BQSKit and NuOp at strictly lower circuit cost. Against Qiskit’s specialized on -family ISAs, GULPS produces identical output circuits – faster, compounding to – on full-circuit transpilation. All decompositions reach the double-precision unitary-infidelity floor. As a byproduct, the continuous formulation yields a Haar-averaged lower bound on expected circuit cost, against which discrete calibration choices can be benchmarked. GULPS is distributed on PyPI and registers as a Qiskit translation-stage plugin.

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