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This paper considers the two-dimensional Cauchy problem of the full compressible Navier-Stokes equations with far-field vacuum in , where the viscosity and heat-conductivity coefficients depend on the absolute temperature in the form of with . Due to the appearance of the vacuum, the momentum equation are both degenerate in the time evolution and spatial dissipation, which makes the study on the well-posedness challenged. By establishing some new singular-weighted (negative powers of the density ) estimates of the solution, we establish the local-in-time well-posedness of the regular solution with far-field vacuum in terms of , the velocity and the entropy .

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