The discovery of superconductivity and correlated electronic phases in twisted bilayer WSe (Xia et al., Nature 2024; Guo et al., Nature 2025) has generated considerable excitement. Accompanying the superconductivity and a correlated insulator phase is the Kondo-lattice-like phenomenology in transport properties. Here we consider how such phenomenology can develop when the combination of the active bands are topological. We advance a unique construction of compact molecular orbitals through a partial Wannierization that is symmetry preserving. The resulting Anderson lattice model provides the basis for a microscopic understanding of the experimental observation, including the involved energy scales. Our approach may apply to a broad range of settings where topology and correlations interplay.

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