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In this paper, we consider the following critical fractional Kirchhoff equation \begin{equation*} \Big(a+b{\int_{^{N}}}|(-Δ)^{\frac{s}{2}}u|^2dx\Big)(-Δ)^su=|u|^{2^_s-2}u,\quad \ ^{N}, \end{equation} where , , and is the fractional Laplacian. We prove the uniqueness and nondegeneracy of positive solutions to the problem, which can be used to study the singular perturbation problems concerning fractional Kirchhoff equations.

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