PSO-UNet: Particle Swarm-Optimized U-Net Framework for Precise Multimodal Brain Tumor Segmentation

Medical image segmentation, particularly for brain tumor analysis, demands precise and computationally efficient models due to the complexity of multimodal MRI datasets and diverse tumor morphologies. This study introduces PSO-UNet, which integrates Particle Swarm Optimization (PSO) with the U-Net architecture for dynamic hyperparameter optimization. Unlike traditional manual tuning or alternative optimization approaches, PSO effectively navigates complex hyperparameter search spaces, explicitly optimizing the number of filters, kernel size, and learning rate. PSO-UNet substantially enhances segmentation performance, achieving Dice Similarity Coefficients (DSC) of 0.9578 and 0.9523 and Intersection over Union (IoU) scores of 0.9194 and 0.9097 on the BraTS 2021 and Figshare datasets, respectively. Moreover, the method reduces computational complexity significantly, utilizing only 7.8 million parameters and executing in approximately 906 seconds, markedly faster than comparable U-Net-based frameworks. These outcomes underscore PSO-UNet’s robust generalization capabilities across diverse MRI modalities and tumor classifications, emphasizing its clinical potential and clear advantages over conventional hyperparameter tuning methods. Future research will explore hybrid optimization strategies and validate the framework against other bio-inspired algorithms to enhance its robustness and scalability.