We provide a mathematical realization of a conjecture by Kitaev, on the basis of the operator-algebraic formulation of infinite quantum spin systems. Our main results are threefold. First, we construct an -spectrum whose homotopy groups are isomorphic to the smooth homotopy group of invertible gapped quantum systems on Euclidean spaces. Second, we develop a model for the homology theory associated with the -spectrum , describing it in terms of the space of quantum systems placed on an arbitrary subspace of a Euclidean space. This involves introducing the concept of localization flow, a semi-infinite path of quantum systems with decaying interaction range, inspired by Yu’s localization C*-algebra in coarse index theory. Third, we incorporate spatial symmetries given by a crystallographic group and define the -spectrum of -invariant invertible phases. We propose a strategy for computing the homotopy group that uses the Davis–Lück assembly map and its description by invertible gapped localization flow. In particular, we show that the assembly map is split injective, and hence contains a computable direct summand.

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