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In 2023, H.,Brezis published a list of his favorite open problems", which he described as challenges he had raised throughout his career and has resisted so far". We provide a complete resolution to the first one–Open Problem 1.1–in Brezis’s favorite open problems list: the existence of solutions to the long-standing Brezis-Nirenberg problem on a three-dimensional ball. Furthermore, using the building blocks of Del Pino-Musso-Pacard-Pistoia sign-changing solutions to the Yamabe problem, we establish the existence of infinitely many sign-changing, nonradial solutions for the full range of the parameter.

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