TeamMedAgents: Pareto-Efficient Multi-Agent Medical Reasoning Through Teamwork Theory

Complex medical reasoning has historically required frontier language models to achieve clinically-acceptable accuracy, creating computational barriers that limit deployment in resource-constrained clinical settings. We present TeamMedAgents, a modular multi-agent framework that translates Salas et al.'s evidence-based teamwork theory into computational mechanisms–shared mental models, team leadership, team orientation, trust networks, and mutual monitoring–enabling Small Language Models to perform multi-step clinical reasoning efficiently. Evaluation across 8 medical benchmarks demonstrates that TeamMedAgents advances the Pareto efficiency frontier by 1-2 orders of magnitude, achieving competitive accuracy at substantially lower token cost than MDAgents, MedAgents, DyLAN, and ReConcile. The framework exhibits the lowest cross-dataset variance among multi-agent approaches, enabling deployment without per-task tuning. Our results establish that theory-grounded coordination mechanisms provide essential scaffolding for deploying efficient medical AI in resource-constrained clinical environments.