In this paper we investigate the Lie algebra structure of the first relative Hochschild cohomology and its relation with the relative notion of fundamental group. Let be finite-dimensional basic -algebras over an algebraically closed field of characteristic zero, such that is a subquiver of . We show that if the complement of by the arrows of is a simple directed graph, then the first relative Hochschild cohomology is a solvable Lie algebra. We also compute the Lie algebra structure of the first relative Hochschild cohomology for radical square zero algebras and for dual extension algebras of directed monomial algebras. Finally, we introduce the notion of fundamental group for a pair of an algebra and a subalgebra and we construct the relative version of the map from the dual fundamental group into the first Hochschild cohomology.

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