The DArk Matter Particle Explorer (DAMPE) is a cosmic-ray detector as well as a pair-converting -ray telescope. The effective area, reflecting the geometrical cross-section area, the -ray conversion probability and the photon selection efficiency, is important in the -ray analyses. In the work, we find a significant time variation in the effective area, as large as at 2 GeV for the high-energy trigger. We derive the data-based correction factors to the effective areas and apply corrections to both the effective areas and the exposure maps. The calibrated exposure can be smaller than the Monte Carlo one on average at 2 GeV. The calibration is further verified using the observation of the Vela pulsar, showing the spectral parameters with the correction are more consistent with those in the Fermi-LAT catalog than the ones without correction. All the corrections are now implemented in the latest version of the DAMPE -ray analysis toolkit DmpST.

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