The paper follows two interconnected directions. 1. Let be a Roelcke precompact closed subgroup of the group of permutations of the natural numbers. Then is closed in , where carries the topology of pointwise convergence for its (faithful) action on the cosets of open subgroups. Under the stronger hypothesis that~ is oligomorphic, is profinite, where denotes the normaliser of~ in , and the topological group is totally disconnected, locally compact. 2a. We provide a general method to show smoothness of the isomorphism relation for appropriate Borel classes of oligomorphic groups. We apply it to two such classes: the oligomorphic groups with no algebraicity, and the oligomorphic groups with finitely many {essential} subgroups up to conjugacy. 2b. Using this method we also show that if is in such a Borel class, then is topologically isomorphic to an oligomorphic group, and is profinite.

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