Let be a metric space with doubling measure and be a nonnegative self-adjoint operator on whose heat kernel satisfies the Gaussian upper bound. We assume that there exists an -harmonic function such that the semigroup , after applying the Doob transform related to , satisfies the upper and lower Gaussian estimates. In this paper we apply the Doob transform and some techniques as in Grafakos-Honzík-Seeger \cite{GHS2006} to obtain an optimal bound in for the maximal function for multipliers with uniform estimates. Based on this, we establish sufficient conditions on the bounded Borel function such that the maximal function is bounded on . The applications include Schrödinger operators with inverse square potential, Scattering operators, Bessel operators and Laplace-Beltrami operators.

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