We study the binding energy differences of the valence proton and neutron of the mirror nuclei, O - N, F - O, Ca - K and Sc - Ca, using the quark-meson coupling model. The calculation involves nuclear structure and shell effects explicitly. It is shown that binding energy differences of a few hundred keV arise from the strong interaction, even after subtracting all electromagnetic corrections. The origin of these differences may be ascribed to the charge symmetry breaking effects set in the strong interaction through the u and d current quark mass difference. In this report, we first review the quark-meson coupling model. In particular, we discuss about the nucleon mass in nuclear medium. Then, we present details of the charge symmetry breaking in finite nuclei, especially the Okamoto-Nolen-Schiffer anomaly.

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