We present a construction, which assigns two groupoids, and , to an inverse semigroup . By definition, is a subgroupoid (even a reduction) of . The construction unifies known constructions for groupoids. More precisely, the groupoid is shown to be isomorphic to the universal groupoid of introduced by Paterson. For arising from graphs resp. tilings, the groupoid is the graph groupoid introduced by Kumjian et al. resp. the tiling groupoid introduced by Kellendonk. We obtain a characterisation of open invariant sets in in terms of certain order ideals of for a large class of (including those arising from graphs and from tilings). If is essentially principal this gives a characterization of the ideal structure of by a theory of Renault. In particular, we then obtain necessary and sufficient conditions on for simplicity of . Our approach relies on a detailed analysis of the order structure of .

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