Let R be a Noetherian domain and let ({\sigma}, {\delta}) be a
quasi-derivation of R such that {\sigma} is an automorphism. There is an
induced quasi-derivation on the classical quotient ring Q of R. Suppose F = t^2
- v is normal in the Ore extension R[t; {\sigma}, {\delta}] where v {\epsilon}
R. We show F is prime in R[t; {\sigma}, {\delta}] if and only if F is
irreducible in Q[t; {\sigma}, {\delta}] if and only if there does not exist w
{\epsilon} Q such that v = {\sigma} (w)w - {\delta} (w). We apply this result
to classify prime quadratic forms in quantum planes and quantized Weyl
algebras.