Experiments conducted by NASA measured the pressure drop due to gas–liquid flow through a packed-bed reactor under microgravity conditions. From these experiments, we develop correlations for the gas–liquid interphase drag in a two-fluid model (TFM). We use an Ergun-type closure for liquid–solid drag. Then, under a 1D flow assumption, is the only unknown in the TFM. Using a data-driven approach, we determine and correlate it (via composite fits) with the liquid and gas Reynolds numbers, and , respectively, and the Suratman number . To validate the proposed closure, we perform two-dimensional transient simulations at microgravity conditions using ANSYS Fluent and employing an Euler–Euler formulation. We find good agreement between the simulations based on the proposed closure and the experimental data.

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