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The -factoriality of a nodal quartic 3-fold implies its non-rationality. We prove that a nodal quartic 3-fold with at most 8 nodes is -factorial, and we show that a nodal quartic 3-fold with 9 nodes is not -factorial if and only if it contains a plane. However, there are non-rational non--factorial nodal quartic 3-folds in . In particular, we prove the non-rationality of a general non--factorial nodal quartic 3-fold that contains either a plane or a smooth del Pezzo surface of degree 4.

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