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We study topological properties of the correspondence of prime spectra associated to a noncommutative ring homomorphism R -> S. Our main result provides criteria for the adjointness of certain functors between the categories of Zariski closed subsets of Spec® and Spec(S); these functors arise naturally from restriction and extension of scalars. When R and S are left noetherian, adjointness occurs only for centralizing and ``nearly centralizing’’ homomorphisms.

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