Several examples of non-compact manifolds whose geometry at infinity is
described by Lie algebras of vector fields (on a
compactification of to a manifold with corners ) were studied by
Melrose and his collaborators. In math.DG/0201202 and math.OA/0211305, the
geometry of manifolds described by Lie algebras of vector fields – baptised
“manifolds with a Lie structure at infinity” there – was studied from an
axiomatic point of view. In this paper, we define and study the algebra
, which is an algebra of pseudodifferential
operators canonically associated to a manifold with the Lie structure at
infinity . We show that many of the properties of the
usual algebra of pseudodifferential operators on a compact manifold extend to
. We also consider the algebra of
differential operators on generated by and , and show that
is a microlocalization'' of $\DiffV{*}(M_0)$. Finally, we introduce and study semi-classical and suspended’’ versions of
the algebra . Our construction solves a problem posed
by Melrose in his talk at the ICM in Kyoto.

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