We study a non-supersymmetric compactification of M-theory on , related to the supersymmetric theory by a chirality flip at one of the boundaries. This system represents an M-theory analog of the D-brane anti-D-brane systems of string theory. Alternatively, this compactification can be viewed as a model of supersymmetry breaking in the ``brane-world’’ approach to phenomenology. We calculate the Casimir energy of the system at large separations, and show that there is an attractive Casimir force between the and boundary. We predict that a tachyonic instability develops at separations of order the Planck scale, and discuss the possibility that the M-theory fivebrane might appear as a topological defect supported by the system. Finally, we analyze the eventual fate of the configuration, in the semiclassical approximation at large separations: the two ends of the world annihilate by nucleating wormholes between the two boundaries.

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