Connection between closeness of classical orbits and the factorization of radial Schr\"{o}dinger equation

It was shown that the Runge-Lenz vector for a hydrogen atom is equivalent to the raising and lowering operators derived from the factorization of radial Schr"{o}dinger equation. Similar situation exists for an isotropic harmonic oscillator. It seems that there may exist intimate relation between the closeness of classical orbits and the factorization of radial Schr"{o}dinger equation. Some discussion was made about the factorization of a 1D Schr"{o}dinger equation.