We analyze uncertainties in the theoretical prediction for the inclusive branching ratio . We find that the dominant uncertainty in the leading order expression comes from its -dependence. We discuss a next-to-leading order calculation of in general terms and check to what extent the -dependence can be reduced in such a calculation. We present constraints on the Standard and Two-Higgs-Doublet Model parameters coming from the measurement of $b \rightarrow s \gamma$ decay. The current theoretical uncertainties do not allow one to definitively restrict the Standard Model parameters much beyond the limits coming from other experiments. The bounds on the Two-Higgs-Doublet Model remain very strong, though significantly weaker than the ones present in the recent literature. In the Two-Higgs-Doublet Model case, the $b \rightarrow s \gammaZ \rightarrow b \bar{b}b \rightarrow c \tau \bar{\nu}{\tau}M{H^{\pm}}-tan \beta$ plane.

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