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Methods are proposed for measuring the ratio $R^{+/0} = \Gamma(\Upsilon(4S) \to B^+ B^-)/$ without assuming isospin invariance in exclusive hadronic decays such as . The validity of isospin invariance in various B decays is discussed. Isospin violations are expected to be especially small in inclusive semileptonic decays, so that is expected to hold at the sub-percent level. Suggestions are made for utilizing this relation. The accuracy of a ``double-tag’’ method for obtaining , such as that used for measuring the ratio at the , is also estimated.

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