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We present a calculation of the next-to-leading order cross section for the inclusive hadroproduction of D and B mesons as a function of the transverse momentum and the rapidity in a massive variable flavor number scheme. We compare our numerical results with recent data from the CDF Collaboration at the Fermilab Tevatron for the production of D^0, D^{*+}, D^+, and D_s^+ mesons at center-of-mass energy TeV and find reasonably good agreement with the measured cross sections.

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