QCD instantons are known to produce deeply bound diquarks. We study whether
it may be used as building blocks in the formation of multiquark states, in
particular pentaquarks and dibaryons.
A simple model is presented in which the lowest scalar diquark (and possibly
the tensor one) can be treated as an independent body'', with the same color and (approximately) the same mass as a constituent (anti)quark. In it a new symmetry exists between states with the same number of bodies’’ but different
number of quarks appear, in particular the 3-``body’’ pentaquarks can be
naturally related to some excited baryons. The limitations of this model are
seen from the fact that it leads to light dibaryon . Another reported work
is based on a calculation of a large set of correlation functions for nonlocal
operators with 4 to 6 light quarks in the Random Instanton Liquid Model (RILM).
The effective interaction between diquarks is studied and found to posses a
strongly {\em repulsive core}, due to the Pauli principle for quark zero modes.

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