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We investigate the isospin chemical potential effect in the frame of SU(2) Nambu-Jona-Lasinio model. When the isospin chemical potential is less than the vacuum pion mass, the phase structure with two chiral phase transition lines does not happen due to breaking of QCD. When the isospin chemical potential is larger than the vacuum pion mass, the ground state of the system is a Bose-Einstein condensate of charged pions.

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