|V_{cb}| and |V_{ub}| Determinations from Inclusive Semileptonic B Decays

The determinations of |V_{cb}| and |V_{ub}| from inclusive semileptonic B decays are reviewed. A comparison of the light-cone approach with the heavy quark expansion approach is made. The perspective for further improvement of the |V_{cb}| and |V_{ub}| determinations is discussed.