We generalize a theorem by Khalfin, originally derived for the states $| F_1
= | M^0>| F_2 > = |\bar M^0>M^0$ is a neutral flavoured meson (e.g., or ), by assuming CPT invariance. Dispensing with CPT invariance and allowing for an arbitrary pair of orthogonal states $| F_{1,2}>| P_a > = p_a | F_1 > + q_a | F_2>| P_b > = p_b | F_1 > - q_b | F_2>$, if postulated to be independently propagating in time, as in the Lee–Oehme–Yang Theory, must be mutually orthogonal. This implies a reciprocity relation: equality of the probabilities of the transitions . Also implied is another relation involving the coefficients , , which can be interpreted as , where is the rephasing-invariant parameter describing CPT violation in mixing for Khalfin’s choice of . The states of \emph{our} theorem need not form a particle-antiparticle pair, nor even be restricted to particle physics.

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