Fundamental time asymmetry from nontrivial space topology

It is argued that a fundamental time asymmetry could arise from the global structure of the space manifold. The proposed mechanism relies on the CPT anomaly of certain chiral gauge theories defined over a multiply connected space manifold. The resulting time asymmetry (microscopic arrow of time) is illustrated by a simple thought experiment. The effect could, in principle, play a role in determining the initial conditions of the big bang.