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We argue that in cuprate physics there are two types, hole content per CuO plane () and the corresponding hole content per unit volume (), of hole-doping concentrations for addressing physical properties that are two-dimensional (2D) and three-dimensional (3D) in nature, respectively. We find that superconducting transition temperature () varies systematically with as a superconducting \textquotedblleft \textquotedblright with a universal optimal hole-doping concentration = 1.6 10 cm for single-layer high temperature superconductors. We suggest that determines the upper bound of the electronic energy of underdoped single-layer high- cuprates.

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