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In this paper, we are devoted to studying the positive weak, punctured or distributional solutions to the biharmonic Lane-Emden equation \begin{equation*} Δ^{2} u=u^{p} \quad \quad \ ^{N}\setminus Z, \end{equation*} where , , and the singular set represents a closed and proper subset of . The symmetry and monotonicity properties of the singular solutions will be given by taking advantage of the moving plane method and the approach of moving spheres.

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