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We review experiments on small-capacitance Josephson junctions. When the Josephson junction is fabricated in the configuration of dc superconducting quantum interference device (SQUID), the Josephson coupling can be tuned IN SITU with an external magnetic field. The electrical transport properties of one-dimensional arrays of small-capacitance dc SQUIDs have been investigated in order to study the superconductor-insulator transition. The arrays have also been used to bias a single Josephson junction, and a clear Coulomb blockade of Cooper-pair tunneling has been observed in the single junction.

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