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In this article we present a system of coupled non-linear PDEs modeling an anisotropic electrokinetic flow. We show the existence of suitable weak solutions in three spatial dimensions, that is weak solutions which fulfill an energy inequality, via a regularized system. The flow is modeled by a Navier–Stokes–Nernst–Planck–Poisson system and the anisotropy is introduced via space dependent diffusion matrices in the Nernst–Planck and Poisson equations.

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