As a basic step for establishing the CO-line Tully-Fisher relation for distant galaxies, we made a comparative study of HI versus CO line profiles. Total line profiles of the CO line emission from 32 galaxies have been compared with the corresponding HI emission. We found a good correlation between the profiles of CO and HI. This strongly supports the thesis that CO can be used in the Tully-Fisher relation for distant galaxies where HI observations cannot reach. We also argue that CO can be used as an alternative to HI for un-isolated galaxies such as those in dense cluster of galaxies. Using the B-magnitudes and a recent calibration of the HI Tully-Fisher relation, we give the distances for the galaxies derived from the CO-line Tully-Fisher relation and compare them with the corresponding HI distances.

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