Advancing Mathematical Epidemic Modeling via synergies with Chemical Reaction Network Theory and Lagrange-Hamilton Geometry

This essay reviews some key concepts in mathematical epidemiology and examines the intersection of this field with related scientific disciplines, such as chemical reaction network theory and Lagrange-Hamilton geometry. Through a synthesis of theoretical insights and practical perspectives, we underscore the significance of essentially non-negative kinetic systems in the development and implementation of robust epidemiological models. Our purpose is to make the case that currently mathematical modeling of epidemiology is focusing too much on simple particular cases, and maybe not enough on more complex models, whose challenges would require cooperation with scientific computing experts and with researchers in the “sister disciplines” involving essentially nonnegative kinetic systems (like virology, ecology, chemical reaction networks, population dynamics, etc).