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In some cosmological theories with varying constants there are anthropic reasons why the expansion of the universe must not be too {\it close} to flatness or the cosmological constant too close to zero. Using exact theories which incorporate time-variations in and in we show how the presence of negative spatial curvature and a positive cosmological constant play an essential role in bringing to an end variations in the scalar fields driving time change in these ‘constants’ during any dust-dominated era of a universe’s expansion. In spatially flat universes with the fine structure constant grows to a value which makes the existence of atoms impossible.

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