The influence of the nuclear symmetry energy on the formation of a mixed quark-nucleon phase in neutron star cores is studied. We use simple parametrizations of the nuclear matter equation of state, and the bag model for the quark phase. The behavior of nucleon matter isobars, which is responsible for the existence of the mixed phase, is investigated. The role of the nuclear symmetry energy changes with the value of the bag constant B. For lower values of B the properties of the mixed phase do not depend strongly on the symmetry energy. For larger B we find that a critical pressure for the first quark droplets to form is strongly dependent on the nuclear symmetry energy, but the pressure at which last nucleons disappear is independent of it.

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