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In this paper, we consider the existence and multiplicity of prescribed mass solutions to the following nonlinear Schrodinger equations with mixed nonlinearities. The standard approach based on the Pohozaev identity to obtain normalized solutions is invalid as the presence of potential. Besides, Our study can be regarded as a Sobolev critical case complement of Bartsch-Qi-Zou (Math Ann 390, 4813-4859, 2024), which has addressed an open problem raised in Bartsch et al.(Commun Partial Differ Equ 46(9):1729–1756,2021).

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